Where to stay when visiting St. Louis has been subject to debate for quite awhile.  I think what everyone agrees on is to stay out of Maryland Heights including the Westport area hotels because of the LE situation.  Now, I know some providers who have successfully worked there without issue but why chance it? Plus most St. Louis guys will shy away from visiting a lady staying in that area regardless of how much she is verified or known etc.    
   
 Some providers feel staying around the airport is best.  I've seen providers in various mid to upscale hotels around there over the years.  Now there has been occasional problems and stings but if you screen and don't create a scene it can be a good area.  The main issues with the airport area in general is not the nicest outside of the nice hotels.  Some places are downright very dangerous.  So if you want to be able to get out of the hotel you'll need transportation to get to the better parts of town.  You definitely don't want to be wandering around that area alone and on foot.  On the other hand if your plan is just to fly in, check in, work for a 2 or 3 days and fly out then it might work for you.  Due to the economic decline of St. Louis and it no longer being a major airline hub, the amount of traveling customers has declined but there are still quite a bit and most local customers will be OK with going to a mid to upscale airport hotel.  
   
 Downtown St. Louis can also be good as long as you know what you are getting into.  There are some very nice hotels downtown that stay busy with traveling business customers.  There are more hotels being built and even more being planned right now.  There are places to go and things to see downtown and a lot are within easy walking distance of the hotels.  BUT there is the crime issue that the city seems unable to deal with unfortunately.  I'd say its a safe place to stay if you don't venture out alone after dark.  My personal hangup with downtown isn't the crime issue but the parking issue which can be an expensive hassle.  Parking and traffic issues especially during baseball season makes it a hassle to see providers staying there, that's my opinion but I think I'm not alone.  Then again, there are providers who report doing well downtown so who knows.  
   
 Forest Park area.  There are some nice hotels and there are things to do and see like the best zoo in the world.  It is centrally located.  I know some providers have stayed in the area but that's about it.  You'll need transportation to get other places if you want to see other sites.  
   
 "West County".  The area has some very nice hotels and very nice shopping districts.  It is upscale suburbia spreading its tentacles further and further west into undeveloped land trying to escape "the city".  It is a nice area but having transportation is a must if you want to get out of the hotel and do anything.  LE can be an issue but again if you stay at a mid to upscale place and screen and don't draw attention to yourself you should be fine.  Chesterfield and Clayton have been known to run stings or try and run suspected escorts out their hotels but not to the extent of Maryland Heights and its usually aimed at problems they become aware of and think they need to deal with.  So if you screen and don't cause problems, you shouldn't have problems.  One issue though is the farther west you go the more guys will whine about you being "too far" away.  Chesterfield is a half hour from the airport or downtown ON A GOOD DAY and longer during rush hour or other traffic entanglements that 64 and 270 seem prone to have.    
   
 That's a general overview from my perspective as a customer, I'm sure there are some experienced providers in the area who can give you more detailed info.