Chicago and Adelita's (AB) are the two best clubs for new dudes.
Depending on when you go and what you want, is where you should be directed to.
Adelita's opens up around 10 am and chicas start to gather around noon and really gets hopping in the later afternoon and keeps going.
Chicago doesn't get going until 8-9-10 pm depending. During the day, you might have 1,2 or 3 girls in Chicago.
More chicas speak some English in AB but the music is so loud, at times, it doesn't matter whether you can speak or not. Best bet is to talk on the top dance floor or at the back dance floor.
I've had one fabulous experience with a true nympho at Chicago and many mediocre sessions.
I've had many great sessions and only a few mediocre sessions at AB so you know my bias.
But there are more average to even some ugly girls (Hey, I'm being honest) at AB. But there are many Hotties in AB too. There was one girl, Sylvia, that was a Christina Applegate (Kelly Bundy) look alike that worked for quite a while at AB. But Sylvia was strictly high volume and was in and out, up and down in record time.

At Chicago, the girls are much thinner and prettier but with that sometimes comes the pricess attitude. Chicago has a much more laid back atmosphere where you can sit and talk and the music is much more bearable on the ears.
Chicago has it's own hotel upstairs, the same with AB and on the alley side, Miami and Hong Kong uses Cascadas hotel.
Some girls will easily show you their health cards and others won't since their real names are on the card.

If this is your first time to the Zone, be safe and take a taxi around, with the exception of when you want to go from AB to Chicago, which you can easily walk in about 40-50 steps.
When you cross the border, you walk up to a taxi and ask to go to either club and pay $5. Anymore, they are trying to rip you off. In Mexico, it's customary to sit up front with the driver. But some drivers will open up the back door for you to sit in the back. The zone has been cleaned up for the past 2-3 years and the daily muggings have stopped since there are quite a few cops around. There's even a cop substation just around the corner. One time, I almost got run over by a car load of cops that came at high speed to an "Officer needs help: radio call. They came within inches of clipping my leg off. As long as you are polite, don't get drunk and stagger around, you should be safe. But even here in the US, you can always have the potential to get mugged, same as Mexico.
My advise is to stay away from any of the aggressive girls that come up to you and either ask you to buy them a drink or take them upstairs.
The girls are usually looking arond to make eye contact with you and if you do, they usually come over to say hello. Most girls don't approach you and will have their spots picked out that they usually hang out at and just sit or stand around. If you are shy, ask a waiter to bring a girl over and tip the guy, usually a buck. Some waiters are good and if you develop a rapport, he may be able to help you out. Other are idiots.
Be careful of your money, I usually have two wads of bills, one that are all $1's and my stash in another place. NEVER flash money around. Sometimes, I'll go in the bathroom stalls to count my money or to arrange it in my different pockets.
If you are going to TJ a lot, it's best if you get a money belt.
There's a few guys floating around in the Zone that speak good English that can act as an intrepeter for you, Texas Mike and Franco. I know Franco, but don't know Texas Mike. Franco most times wears a hat or beret and hangs near the corner of Constitucion and Coahuilla but he's everywhere, just trying to make a buck.            
It all depends on what you are wanting from TJ. If you want to have sex with a girl that has a smoking hot body and face, you can get her for usually $60 for a half hour. If you're looking for a GFE, that's much more difficult to find.
If you don't mind spending more money, you can also go to the many massage parlors around TJ. The girls are usually much better looking but the negatives are that you usually have only the massage table and the price is usually for "everything" around $120-150 which still is good but close to or above US MP prices.
For all the years I've been going to TJ, I have thought about going but have never been to the MP's except a great legit one.

If you have specific questions beyond what I've posted, PM me.

AB and CC are definitely both great spots to meet the perfect chica.  Both have a problem with the hotels.  When you pay your $11. for a room it is supposed to be for 30 minutes but the guys generally knock on the door between 15 and 20 minutes.  The hotel above AB is the worst about this.  I told them I would never come back the last time this happened.  You can also pay an extra ten to get the room for an hour.  Another great bar which is quickly becoming my favorite is Tropical which is across the street from AB.  They have some great dancers and the hotel is much more accomodating.  If you go to the Tropical be sure to ask for Mario the mesero (waiter).  He has worked in the US and speaks perfect English.  He will help you to meet the girl of your choice.

If you want to have a GFE you will need to ask the chica some questions:  DFK Tu besa con la lingua?; DATY setenta y nueve? and BBBJ chupa sin condon?

You can also arrange for a TLN todo de noche and the girl will go back to your hotel and spend the night; usually for $100. to $150.  If you really are enjoying a chica's company, take her to dinner and dancing.  Your mileage will increase exponentially.

Good luck and remember TJ is a playground for all to enjoy!

Be careful that a girl does not try to "fake" having sex!  Believe it or not a girl can get away with this in a dimly lit room and
using clever hand placement.  Make sure she does not use her hands
to cover areas of interest.  

One question I have, if you catch a girl trying to do this, what do you do?  It seems to me that trying to get your money back or raising a stink with the club would only get you thrown out or worse tossed in jail.  Is there a way to let it be known that a girl is a thief and cheat, as well as a wh...?